Description

1,2-Ditetradecylphosphatidylcholine is a synthetic, saturated phospholipid with a defined C14 (myristyl) fatty acid chain length. This high-purity, single-component lipid is critical for creating stable, well-defined model membrane systems and advanced lipid-based formulations. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over lipid composition for consistent and reproducible results.

Application

• Liposome & Nanoparticle Formulation: A key structural component for creating unilamellar vesicles (LUVs, SUVs) and solid lipid nanoparticles (SLNs) with high phase transition temperature and stability.
• Biomimetic Membrane Research: Used to construct supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) for fundamental studies of membrane protein function, permeability, and biophysical properties.
• Drug Delivery Systems: Serves as a primary excipient in the development of liposomal drug carriers for targeted and sustained release applications, enhancing drug encapsulation efficiency.
• Diagnostic Reagents: Employed in the formulation of stable emulsion-based reagents and calibrators for clinical diagnostic assays.
• Biophysical & Analytical Standards: Acts as a high-purity reference standard in chromatography (HPLC, LC-MS) and spectroscopy for quality control and method development.
• Crystallography & Structural Biology: Provides a defined lipid environment for the solubilization, stabilization, and crystallization of membrane proteins.

Basic Information

Product Name	1,2-Ditetradecylphosphatidylcholine
CAS No.	69483-38-1
Molecular Formula	C36H74NO8P
Molecular Weight	679.95 g/mol
Synonyms	DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine); 1,2-Dimyristoylphosphatidylcholine; PC(14:0/14:0); Ditetradecanoylphosphatidylcholine; Phosphatidylcholine, 1,2-ditetradecanoyl; 3-sn-Phosphatidylcholine, 1,2-dimyristoyl; L-α-Phosphatidylcholine, dimyristoyl; 1,2-Di(tetradecanoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Ditetradecylphosphatidylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Lyso-Impurity (HPLC)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%
Phase Transition Temperature (DSC)	Approx. 23-24°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.