Description

L-Phenylalanine Dehydrogenase is a highly specific oxidoreductase enzyme that catalyzes the reversible deamination of L-phenylalanine to phenylpyruvate. This specificity makes it an invaluable biocatalyst for the stereoselective synthesis and analytical determination of chiral amino acids. It is essential for manufacturers and researchers in the pharmaceutical, diagnostic, and fine chemical industries requiring high-precision enzymatic processes for chiral resolution, biosensor development, and metabolic pathway analysis.

Application

• Pharmaceutical Intermediate Synthesis: Key biocatalyst for the enantioselective production of L-phenylalanine and related non-natural amino acids used in API manufacturing.
• Diagnostic Kits & Biosensors: Core enzyme component in clinical diagnostic assays and biosensors for the quantitative detection of phenylalanine, crucial for newborn screening of phenylketonuria (PKU).
• Biocatalysis & Process Development: Used in enzymatic cascade reactions and green chemistry applications for the sustainable synthesis of chiral amines and fine chemicals.
• Research & Biochemical Analysis: Essential tool in enzymology research, metabolic studies, and as a reagent for the spectrophotometric determination of L-phenylalanine concentration in various samples.
• Food & Nutraceutical Analysis: Employed in quality control laboratories for the accurate quantification of amino acids in foodstuffs, supplements, and nutraceutical products.

Basic Information

Product Name	L-Phenylalanine Dehydrogenase
CAS No.	69403-12-9
Molecular Formula	Information available on request
Molecular Weight	Information available on request
Synonyms	PheDH; L-PheDH; L-Phenylalanine:NAD+ Oxidoreductase (deaminating); EC 1.4.1.20; NAD+-L-Phenylalanine Dehydrogenase; Phenylalanine Dehydrogenase (L-); L-Phenylalanine Dehydrogenase (NAD)
EINECS	Contact for details

Quality Control

Our L-Phenylalanine Dehydrogenase is produced and tested under a rigorous quality management system. Each batch is characterized for critical parameters including specific activity, purity (by SDS-PAGE), and stability to ensure consistent, reliable performance in sensitive applications. A comprehensive Certificate of Analysis (COA) detailing assay results, storage buffer, and unit definition is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after use to prevent moisture uptake.

Specification

Item	Specification
Appearance	Clear to slightly opalescent solution
Identification (Activity)	Catalyzes the specific deamination of L-Phenylalanine
Specific Activity	≥ [Value] U/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	~ [Value] mg/mL
Storage Buffer	Potassium phosphate, glycerol, pH ~7.2
Stability	≥ 12 months at -20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.