Description

Biotin-Propranolol Analogue CAS NO 69079-54-5 is a specialized synthetic compound designed as a molecular probe for biochemical and pharmacological research. This analogue is strategically engineered to leverage the high-affinity binding of biotin with the β-adrenergic receptor antagonism of propranolol, creating a powerful tool for targeted studies. It is primarily utilized by research scientists and pharmaceutical developers in the fields of molecular biology, neuropharmacology, and targeted drug delivery.

Application

• Biochemical Research Probe: Used in affinity chromatography and pull-down assays to isolate and study β-adrenergic receptor complexes and associated proteins.
• Targeted Drug Delivery Studies: Serves as a model compound for investigating ligand-directed delivery systems, where biotin acts as a targeting moiety.
• Receptor Mapping and Imaging: Facilitates the localization and visualization of adrenergic receptors in cell cultures and tissue samples via biotin-streptavidin detection systems.
• Pharmacological Mechanism Elucidation: Aids in studying the structure-activity relationships (SAR) of propranolol derivatives and their interaction pathways.
• Prototype for Diagnostic Agent Development: Provides a foundational structure for creating novel diagnostic agents targeting cardiovascular or neurological systems.
• Academic and Industrial R&D: Essential for basic research in university laboratories and for early-stage drug discovery programs in biotech and pharmaceutical companies.

Basic Information

Item	Detail
Product Name	Biotin-Propranolol Analogue
CAS No.	69079-54-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotinylated Propranolol; Propranolol-Biotin Conjugate; Biotin-Propranolol Conjugate; N-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N'-(1-(naphthalen-1-yloxy)-3-((propan-2-yl)amino)propan-2-yl)pentanediamide (IUPAC); Biotin-Propranolol Hybrid Molecule; β-blocker Biotin Tag; Research Grade Biotin-Propranolol
EINECS	Contact for details

Quality Control

Our Biotin-Propranolol Analogue is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your compliance and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.