Description

Uroporphyrin I Dihydrochloride is a high-purity porphyrin derivative essential for biochemical research and diagnostic applications. This compound serves as a critical reference standard and biochemical tool for studying heme biosynthesis and related metabolic disorders. It is primarily utilized by research institutions, diagnostic laboratories, and pharmaceutical developers focused on porphyrias, enzymology, and metabolic pathway analysis.

Application

• Biochemical Research: Used as a key substrate and reference standard in enzymatic studies of uroporphyrinogen decarboxylase and other enzymes in the heme biosynthesis pathway.
• Diagnostic Development: Serves as a critical calibrator and control material in the development and validation of diagnostic assays for porphyria diseases.
• Metabolic Studies: Employed in in vitro and cellular models to investigate porphyrin metabolism, accumulation, and associated cellular toxicity.
• Pharmaceutical R&D: Acts as a reference compound for drug discovery programs targeting heme-related disorders and for testing potential therapeutic agents.
• Analytical Chemistry: Used as a high-purity standard for HPLC, LC-MS, and other chromatographic methods to quantify porphyrins in biological samples.
• Educational Purposes: Supplied to universities and teaching laboratories for advanced courses in biochemistry, metabolism, and clinical chemistry.

Basic Information

Product Name	Uroporphyrin I Dihydrochloride
CAS No.	68929-06-6
Molecular Formula	C₄₀H₄₂N₄O₁₆·2HCl
Molecular Weight	869.70 g/mol
Synonyms	Uroporphyrin I dihydrochloride; Uroporphyrin I HCl; Uroporphyrin I, dihydrochloride; 3,7,13,17-Tetrakis(2-carboxyethyl)-2,8,12,18-tetramethylporphyrin-21,23-diium dihydrochloride; URO I dihydrochloride; Uroporphyrinogen I oxidation product dihydrochloride; Porphyrin I, Uro-, dihydrochloride
EINECS	Contact for details

Quality Control

Our Uroporphyrin I Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic identification (UV-Vis), to ensure it meets the stringent requirements for research and diagnostic use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (UV-Vis)	Conforms
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in dilute alkali, DMSO; Slightly soluble in water
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.