Description

(5α,25α)-8,9-Didehydrocevane-3α,6β,20-Triol is a steroidal alkaloid derivative belonging to the cevane family, characterized by its specific hydroxylation pattern and unsaturated bond. This compound is of significant interest in advanced pharmaceutical research and development due to its complex structure, which serves as a key intermediate or reference standard for the synthesis of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in steroid chemistry, medicinal chemistry, and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex steroid-based drugs and novel therapeutic candidates.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development, validation, and compound identification via HPLC, LC-MS, or NMR.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles for new drug discovery programs.
• Biochemical Research: Utilized as a tool compound in pharmacological studies to investigate interactions with biological targets and pathways related to steroid signaling.
• Fine Chemical Synthesis: Acts as a specialized starting material for the custom synthesis of other high-value, complex natural product derivatives and analogs.

Basic Information

Product Name	(5α,25α)-8,9-Didehydrocevane-3α,6β,20-Triol
CAS No.	68676-58-4
Molecular Formula	C27H45NO3
Molecular Weight	431.66 g/mol
Synonyms	8,9-Didehydrocevane-3α,6β,20-triol, (5α,25α)-; 3α,6β,20-Trihydroxy-5α,25α-cevane-8-ene; Ceva-8-ene-3α,6β,20-triol, (5α,25α)-; Veratramine triol derivative; Steroidal alkaloid triol; Cevane alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (5α,25α)-8,9-Didehydrocevane-3α,6β,20-Triol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing all test results and specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.