Description

Bis(2-Oxo-3-Oxazolidinyl)Phosphinic Chloride is a versatile and highly reactive organophosphorus compound, primarily valued as a key intermediate in the synthesis of advanced pharmaceutical agents and specialty chemicals. Its unique structure makes it an essential building block for introducing the phosphinic acid moiety into complex molecules, enabling the development of novel bioactive compounds. This product is critical for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to create innovative active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing protease inhibitors, antiviral drugs, and other bioactive molecules containing phosphinic acid groups.
• Peptidomimetic Synthesis: Used in the preparation of transition-state analog inhibitors that mimic peptide substrates for enzymes like renin and HIV protease.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and plant growth regulators with targeted modes of action.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized phosphinate-based ligands for catalytic applications.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with specific thermal or chemical resistance properties.
• Bioconjugation Chemistry: Useful for modifying biomolecules (proteins, peptides) by introducing stable phosphinate linkages.

Basic Information

Product Name	Bis(2-Oxo-3-Oxazolidinyl)Phosphinic Chloride
CAS No.	68641-49-6
Molecular Formula	C6H7ClN2O4P
Molecular Weight	238.56 g/mol
Synonyms	BOP-Cl; Bis(2-oxo-3-oxazolidinyl)phosphinic chloride; (Oxo-1,3-oxazolidin-3-yl)phosphonic chloride; 1,3-Oxazolidin-2-one, 3,3'-(phosphinylidene)bis-, chloride; Phosphorochloridic acid, P,P-bis(2-oxo-3-oxazolidinyl)-; NSC 339243
EINECS	Contact for details

Quality Control

Our Bis(2-Oxo-3-Oxazolidinyl)Phosphinic Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.