Description

Hydroxylapatite is a naturally occurring mineral form of calcium apatite and a key inorganic constituent of bone and dental enamel. Its exceptional biocompatibility and bioactive properties make it a cornerstone material for advanced medical and industrial applications. This high-purity synthetic grade is essential for manufacturers in the biomedical, dental, chromatography, and environmental sectors seeking reliable, consistent performance.

Application

• Biomedical & Dental Implants: Primary material for bone graft substitutes, coatings for metallic implants to enhance osteointegration, and bioactive fillers in dental composites and cements.
• Chromatography Media: Used as a stationary phase in high-performance liquid chromatography (HPLC) and column chromatography for the purification of proteins, nucleic acids, and other biomolecules.
• Cosmetics & Personal Care: Acts as a gentle, biocompatible abrasive in toothpastes and as an opacifying or bulking agent in premium cosmetic formulations.
• Environmental Remediation: Effective adsorbent for the removal of heavy metal ions (e.g., lead, cadmium) and fluoride from contaminated water streams.
• Bioceramics & 3D Printing: Feedstock powder for fabricating porous scaffolds in tissue engineering and additive manufacturing (3D printing) of patient-specific implants.
• Research & Development: Standard reference material and substrate for studies in biomimetics, biomineralization, and surface science.

Basic Information

Product Name	Hydroxylapatite
CAS No.	68439-86-1
Molecular Formula	Ca5(PO4)3(OH)
Molecular Weight	502.31 g/mol
Synonyms	Hydroxyapatite; HAP; Calcium Hydroxylapatite; Calcium Phosphate Hydroxide; Durapatite; Bone Apatite; Calcium Hydroxyapatite; Tribasic Calcium Phosphate (specific form); Ca10(PO4)6(OH)2
EINECS	270-425-2

Quality Control

Our Hydroxylapatite is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing to ensure it meets stringent specifications for purity, crystallinity, particle size, and surface area. Certificates of Analysis (COA) detailing these parameters are provided with every shipment. We can supply grades suitable for research, industrial, and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed after use to prevent absorption of atmospheric moisture and CO2.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (as Ca5(PO4)3(OH))	≥ 96.0 %
Calcium (Ca) Content	36.0 - 40.0 %
Phosphorus (P) Content	17.0 - 19.0 %
Ca/P Molar Ratio	1.65 - 1.70
Crystallinity (by XRD)	≥ 90 %
Heavy Metals (as Pb)	≤ 10 ppm
Loss on Ignition	≤ 2.0 %
Specific Surface Area (BET)	40 - 100 m²/g (grade dependent)
Average Particle Size (D50)	1 - 50 µm (grade dependent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.