Description

8α-Acetoxy-2-O,9-o-Dideacetyl-9-o-(2-Acetoxy-2-Methylpropionyl)-8-Deoxoevonine CAS NO 68419-27-2 is a high-purity, semi-synthetic derivative of the evonine alkaloid class, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its specific functionalization, which makes it a versatile building block for the synthesis of novel bioactive compounds targeting complex therapeutic pathways. This product is essential for research institutions and pharmaceutical companies focused on oncology, neurology, and metabolic disease drug discovery, where precise molecular scaffolds are required.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel evonine-based therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Oncology Drug Discovery: Investigated for the development of potential anti-cancer compounds due to the biological activity profile of the evonine core.
• Neurological Agent Synthesis: Employed in research programs aimed at creating new neuroactive or neuroprotective molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Biochemical Tool Compound: Utilized in vitro to study specific biological pathways and mechanisms of action.

Basic Information

Product Name	8α-Acetoxy-2-O,9-o-Dideacetyl-9-o-(2-Acetoxy-2-Methylpropionyl)-8-Deoxoevonine
CAS No.	68419-27-2
Molecular Formula	C31H43NO11
Molecular Weight	605.68 g/mol
Synonyms	8-Deoxoevonine, 9-(2-Acetoxy-2-methyl-1-oxopropoxy)-8α-(acetyloxy)-2,9-dideacetyl-; 8α-Acetoxy-2,9-dideacetyl-9-(2-acetoxy-2-methylpropionyl)-8-deoxoevonine; Evonine derivative; 8-Deoxoevonine intermediate; CAS 68419-27-2
EINECS	Contact for details

Quality Control

Our 8α-Acetoxy-2-O,9-o-Dideacetyl-9-o-(2-Acetoxy-2-Methylpropionyl)-8-Deoxoevonine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our analytical methods, including HPLC and NMR, are validated to provide reliable and accurate data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.