Description

10-Oxo Morphine is a specialized morphine derivative and a key synthetic intermediate in advanced pharmaceutical research. This compound is of significant interest for its role in the development of novel analgesics and for studying metabolic pathways and structure-activity relationships of opioid compounds. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of controlled substance analogs for therapeutic and investigative purposes. The product is supplied with a focus on high purity and reliable documentation to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of novel opioid-based analgesic agents and their derivatives.
• Metabolic Studies: Used as a reference standard or metabolite analog in pharmacokinetic and pharmacodynamic research related to morphine and its analogs.
• Medicinal Chemistry Research: Serves as a building block for exploring new chemical entities and modifying the opioid core structure to alter potency, selectivity, or metabolic profile.
• Analytical Reference Standard: Employed in qualitative and quantitative analysis (e.g., HPLC, GC-MS) for method development and validation in forensic and clinical laboratories.
• Biochemical Research: Utilized in studies investigating opioid receptor interactions, signal transduction pathways, and enzyme inhibition.
• Controlled Substance Synthesis: An important intermediate for the licensed, compliant manufacture of specific scheduled pharmaceutical compounds.

Basic Information

Product Name	10-Oxo Morphine
CAS No.	68254-48-8
Molecular Formula	C₁₇H₁₉NO₄
Molecular Weight	301.34 g/mol
Synonyms	10-Oxomorphine; Morphine, 10-oxo-; 10-Ketomorphine; 7,8-Didehydro-4,5α-epoxy-17-methylmorphinan-3,6α,10-triol-10-one; 10-Oxo-7,8-didehydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol
EINECS	Contact for details

Quality Control

Every batch of 10-Oxo Morphine is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for key parameters including assay, related substances, and residual solvents, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.