Description

Berberine Chloride Hydrate is a quaternary ammonium salt of the benzylisoquinoline alkaloid berberine. This compound is valued for its significant biological activity and serves as a key reference standard and active ingredient in research and development. It is primarily sought by the pharmaceutical, nutraceutical, and life science research industries for applications ranging from metabolic health to microbiological studies. Our supply ensures high purity and batch-to-batch consistency for critical industrial and research needs.

Application

• Pharmaceutical intermediate for the synthesis of metabolic and cardiovascular drugs.
• Reference standard for analytical testing and quality control in pharmaceutical and nutraceutical manufacturing.
• Active pharmaceutical ingredient (API) in dietary supplements targeting blood sugar and lipid metabolism.
• Biochemical research reagent for studying cellular signaling pathways, including AMPK activation.
• Starting material for the preparation of other berberine derivatives and salts.
• Ingredient in veterinary health products.
• Component in in-vitro diagnostic assays.
• Model compound for studying the properties of plant-derived alkaloids.

Basic Information

Product Name	Berberine Chloride Hydrate
CAS No.	68030-18-2
Molecular Formula	C20H18ClNO4 · xH2O
Molecular Weight	371.81 (Anhydrous basis)
Synonyms	Berberine HCl Hydrate; Berberine Hydrochloride Hydrate; Umbellatine Chloride Hydrate; Natural Yellow 18 Chloride Hydrate; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride Hydrate; Berberine Chloride; Berberinium Chloride Hydrate
EINECS	Contact for details

Quality Control

Our Berberine Chloride Hydrate is manufactured under a strict quality management system. Each batch is tested to ensure identity, purity, and consistency, meeting specifications suitable for research and industrial use. Certificates of Analysis (COA) detailing results for assay, related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 8.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.