Description

4-Methylumbelliferyl α-D-Galacturonic Acid is a specialized fluorogenic substrate used for the detection and quantification of enzymatic activity. This compound is critical for research and diagnostic applications where precise measurement of α-galacturonidase or related enzymes is required. It is primarily utilized by biotech and pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on carbohydrate chemistry and enzymology.

Application

• Enzyme Activity Assays: As a fluorogenic substrate for the sensitive detection and kinetic study of α-galacturonidase and pectin-degrading enzymes.
• Diagnostic Development: A key component in the formulation of diagnostic kits for enzyme deficiency disorders and microbiological testing.
• Biochemical Research: Used in studies of pectin metabolism, plant cell wall degradation, and microbial pathogenesis.
• High-Throughput Screening (HTS): Employed in pharmaceutical and agrochemical discovery for screening enzyme inhibitors or activators.
• Food Science & Quality Control: Applied in assays to monitor pectinase activity during food processing (e.g., juice clarification).
• Industrial Enzyme Characterization: Used to assess the purity and specific activity of commercial enzyme preparations.

Basic Information

Product Name	4-Methylumbelliferyl α-D-Galacturonic Acid
CAS No.	67968-37-0
Molecular Formula	C₁₆H₁₆O₁₀
Molecular Weight	368.29 g/mol
Synonyms	4-MU-α-D-Galacturonic Acid; 4-Methylumbelliferyl-α-D-galactopyranuronic acid; 4-Methylumbelliferyl α-D-galactopyranosiduronic acid; 4-MU-α-GalA; α-D-Galacturonic acid 4-methylumbelliferyl ester; 4-Methyl-7-hydroxycoumarin α-D-galacturonide; Fluorogenic galacturonic acid substrate
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl α-D-Galacturonic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay conditions. We adhere to ISO 9001 quality management principles, and our production environment is designed to meet the needs of GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light will degrade performance. For long-term storage, consider desiccant and under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Fluorogenic Activity	Conforms (in standard assay)
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.