Description

5,7-Dihydroxy-1-(3,4,5-Trimethoxybenzyl)-1,2,3,4-Tetrahydroisoquinoline is a specialized synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex bioactive molecules, particularly within pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct novel tetrahydroisoquinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting neurological or cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Alkaloid Synthesis: Used in the semi-synthesis or total synthesis of complex natural products and alkaloids containing the tetrahydroisoquinoline moiety.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding activities.
• Agrochemical Research: Acts as an intermediate in the development of novel crop protection agents and pesticides.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Item	Details
Product Name	5,7-Dihydroxy-1-(3,4,5-Trimethoxybenzyl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	67950-89-4
Molecular Formula	C19H23NO5
Molecular Weight	345.39 g/mol
Synonyms	1-(3,4,5-Trimethoxybenzyl)-5,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; 5,7-Dihydroxy-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5,7-dihydroxy-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinoline; THIQ derivative; Trimethoxybenzyl-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 5,7-Dihydroxy-1-(3,4,5-Trimethoxybenzyl)-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry environment. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.