Description

2-Methacryloyloxyethyl Phosphorylcholine (CAS NO 67881-98-5) is a high-purity, functional methacrylate monomer containing a biomimetic phosphorylcholine group. This compound is critical for imparting exceptional biocompatibility and non-fouling properties to synthetic polymer surfaces. It is an essential raw material for manufacturers in the biomedical, pharmaceutical, and advanced materials sectors seeking to create hemocompatible, protein-resistant, or anti-biofouling coatings and hydrogels.

Application

• Biomedical Device Coatings: Key monomer for creating non-thrombogenic, hemocompatible surfaces on cardiovascular stents, catheters, blood-contacting implants, and oxygenators.
• Contact Lens & Ophthalmic Materials: Used to formulate hydrogel polymers for soft contact lenses and intraocular lenses to improve wettability, comfort, and reduce protein/lipid deposition.
• Anti-Biofouling Surfaces: Incorporated into marine coatings, biosensor interfaces, and filtration membranes to prevent the adhesion of proteins, cells, and microorganisms.
• Drug Delivery Systems: Serves as a building block for synthesizing stimuli-responsive or stealth polymer carriers (e.g., micelles, nanoparticles) for targeted and sustained drug release.
• Tissue Engineering Scaffolds: Used to fabricate biocompatible and cell-friendly hydrogel scaffolds that mimic the natural extracellular matrix for regenerative medicine.
• Diagnostic Assays: Applied to modify microfluidic channels and assay platforms to minimize non-specific binding, enhancing signal-to-noise ratios in diagnostic tests.

Basic Information

Product Name	2-Methacryloyloxyethyl Phosphorylcholine
CAS No.	67881-98-5
Molecular Formula	C11H22NO6P
Molecular Weight	295.27 g/mol
Synonyms	MPC; 2-Methacryloyloxyethyl Phosphorylcholine; 2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate; Phosphorylcholine methacrylate; MPC Monomer; 2-Methacryloxyethyl Phosphorylcholine; Lipidure™ monomer; L-MPC
EINECS	Contact for details

Quality Control

Our 2-Methacryloyloxyethyl Phosphorylcholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the stringent requirements for biomedical and pharmaceutical applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and prevent polymerization. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Inhibitor (MEHQ)	50 - 250 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.