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Rac-1,2-Dipalmitoyl-Glycero-3-Phosphocholine Monohydrate CAS NO 67533-10-2


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CAS No.:67533-10-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rac-1,2-Dipalmitoyl-Glycero-3-Phosphocholine Monohydrate is a synthetic phospholipid, specifically a racemic mixture of dipalmitoyl phosphatidylcholine (DPPC) with a monohydrate crystal structure. This compound is a critical model membrane lipid and a key component for studying lipid bilayer properties, membrane fluidity, and biophysical interactions. It is essential for researchers and manufacturers in pharmaceutical development, liposome formulation, and advanced biomaterial research.

Application

  • Liposome & Drug Delivery System Formulation: As a primary phospholipid component for creating stable, uniform liposomes for targeted drug delivery.
  • Biophysical & Membrane Research: Used as a standard model membrane lipid to study phase transitions, permeability, and the behavior of lipid bilayers.
  • Pharmaceutical Excipient: Employed in the development of parenteral and pulmonary drug products where controlled release and biocompatibility are required.
  • Biomimetic Coatings & Materials: Serves as a building block for creating synthetic cell membranes and biocompatible surface coatings for medical devices.
  • Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products for its emollient and skin-barrier enhancing properties.
  • Diagnostic Reagent Preparation: Used in the manufacture of reagents and standards for clinical diagnostics and analytical testing.

Basic Information

Product Name Rac-1,2-Dipalmitoyl-Glycero-3-Phosphocholine Monohydrate
CAS No. 67533-10-2
Molecular Formula C40H82NO8P • H2O
Molecular Weight 758.06 g/mol (Anhydrous basis: 740.04)
Synonyms DPPC, Racemic DPPC; 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine (racemic); (±)-DPPC; Phosphatidylcholine, 1,2-dipalmitoyl- (racemic); L-α-Phosphatidylcholine, dipalmitoyl- (racemic); 3-sn-Phosphatidylcholine, 1,2-dipalmitoyl- (racemic); Palmitoylphosphatidylcholine (racemic); Lecithin, dipalmitoyl- (racemic)
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Quality Control

Our Rac-1,2-Dipalmitoyl-Glycero-3-Phosphocholine Monohydrate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, TLC for lipid profiling, and NMR for structural confirmation, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) with detailed chromatograms and full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) 3.0 - 6.0% (Theoretical for monohydrate: ~2.4%)
Residual Solvents (GC) Meets ICH guidelines
Phase Transition Temperature (DSC) Approx. 41°C
Heavy Metals < 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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