Description

Benoxaprofen Glucuronide is a key metabolite of the non-steroidal anti-inflammatory drug (NSAID) benoxaprofen. This compound is of significant value in pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and toxicology. It serves as a critical reference standard for analytical laboratories in pharmaceutical, biotechnology, and contract research organizations (CROs) requiring precise quantification and identification of benoxaprofen and its metabolic pathways.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and validation of methods in drug testing.
• Metabolite Identification & Profiling: Essential for in-vitro and in-vivo studies to map the metabolic fate of benoxaprofen, aiding in drug safety assessments.
• Bioanalytical Method Development: Serves as a critical component in developing and validating HPLC, LC-MS, or GC-MS assays for pharmacokinetic studies.
• Toxicology Research: Used to investigate the role of glucuronidation in the detoxification or potential bioactivation of benoxaprofen.
• Quality Control in API Manufacturing: Employed as an impurity standard to monitor and control the quality of benoxaprofen active pharmaceutical ingredient (API) batches.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry, enzymology (UGT studies), and metabolic engineering.

Basic Information

Product Name	Benoxaprofen Glucuronide
CAS No.	67472-42-8
Molecular Formula	C24H25NO9
Molecular Weight	471.46 g/mol
Synonyms	Benoxaprofen β-D-Glucuronide; 2-(4-Chlorophenyl)-α-methyl-5-benzoxazoleacetic acid β-D-glucopyranosiduronic acid; Benoxaprofen 1-O-β-Acid Glucuronide; Benoxaprofen Glucuronide Conjugate; Benoxaprofen Acyl Glucuronide; Opren Glucuronide; MJ 19810 Glucuronide
EINECS	Contact for details

Quality Control

Our Benoxaprofen Glucuronide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and reference applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.