Description

Methyl 7-Hydroxy-3-Ketocholanoate is a high-purity steroidal derivative and a key synthetic intermediate in organic chemistry. This compound matters for its role as a versatile building block in the synthesis of complex bioactive molecules, offering precise structural control. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions developing novel therapeutic agents and studying metabolic pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel bile acid analogs and steroidal drugs targeting metabolic and liver disorders.
• Research & Development: Used as a reference standard and a key starting material in academic and industrial research exploring cholesterol metabolism and related biochemical pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex molecular architectures in custom synthesis and process development.
• Biochemical Studies: Employed in enzymatic and receptor-binding studies to investigate the interaction of modified bile acid structures.

Basic Information

Product Name	Methyl 7-Hydroxy-3-Ketocholanoate
CAS No.	67371-28-2
Molecular Formula	C25H40O4
Molecular Weight	404.59 g/mol
Synonyms	Methyl 7α-Hydroxy-3-oxocholanoate; 7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid Methyl Ester; 3-Keto-7α-hydroxy-5β-cholan-24-oic Acid Methyl Ester; 7-Hydroxy-3-ketocholanoic Acid Methyl Ester; Methyl 3-Keto-7α-hydroxy-5β-cholanate; 5β-Cholan-24-oic Acid, 7α-Hydroxy-3-oxo-, Methyl Ester; 7α-Hydroxy-3-oxocholanic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 7-Hydroxy-3-Ketocholanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.