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Uridine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester CAS NO 67341-43-9
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CAS No.:67341-43-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Uridine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester is a high-purity, fluorinated nucleotide sugar derivative, serving as a critical biochemical precursor and research reagent. Its primary value lies in its role as a key intermediate in the synthesis of fluorinated analogs for metabolic studies and diagnostic tracer development. This compound is essential for researchers and manufacturers in the fields of radiopharmaceuticals, molecular biology, and oncology research, where precise biochemical tools are required.
Application
- Radiopharmaceutical Precursor: A key intermediate in the synthesis of positron emission tomography (PET) imaging agents, particularly for metabolic tracer development.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate carbohydrate metabolism and nucleotide sugar pathways.
- Oncology Research: Employed in the development of novel therapeutic agents and diagnostic probes targeting cancer cell metabolism.
- Glycobiology Studies: Serves as a specialized building block for synthesizing fluorinated glycoconjugates and studying glycosylation processes.
- Antiviral/Anticancer Agent Development: Investigated as a potential intermediate for prodrugs or active pharmaceutical ingredients (APIs) in targeted therapies.
- Enzyme Kinetics & Mechanism: Utilized to probe the active sites and catalytic mechanisms of glycosyltransferases and related enzymes.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Uridine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester |
| CAS No. | 67341-43-9 |
| Molecular Formula | C15H22FN2O16P2 |
| Molecular Weight | 558.28 g/mol |
| Synonyms | 2'-Deoxy-2'-fluorouridine diphosphate glucose; 2'-F-2'-dUDP-Glucose; UDP-2-Deoxy-2-fluoro-D-glucose; 2'-Fluoro-2'-deoxyuridine diphosphoglucose; Fluorinated UDP-glucose analog; 2-F-dUDPG; Uridine 5'-(2-deoxy-2-fluoro-D-glucopyranosyl diphosphate); 67341-43-9 |
| EINECS | Contact for details |
Quality Control
Our Uridine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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