Description

3',5'-Diamino-3',5'-Dideoxyadenosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel oligonucleotides and nucleotide-based therapeutics, offering unique structural modifications that can enhance stability and biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, antisense oligonucleotides, and other targeted molecular therapies. The product is supplied with a guaranteed Certificate of Analysis to ensure research integrity and reproducibility.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Antisense Oligonucleotide (ASO) Synthesis: Used as a modified building block to create oligonucleotides with enhanced nuclease resistance and binding affinity.
• Biochemical Research: Employed in studies investigating nucleoside metabolism, enzyme mechanisms, and structure-activity relationships (SAR).
• Prodrug Development: Serves as a scaffold for designing prodrugs aimed at improving cellular uptake and targeted delivery.
• Molecular Biology Probes: Utilized in the creation of labeled probes for diagnostic assays and genomic research.
• Academic & Industrial R&D: Fundamental material for exploratory chemistry in universities and corporate R&D laboratories focusing on nucleic acid chemistry.

Basic Information

Product Name	3',5'-Diamino-3',5'-Dideoxyadenosine
CAS No.	67313-23-9
Molecular Formula	C10H15N7O2
Molecular Weight	265.27 g/mol
Synonyms	3',5'-Diamino-3',5'-dideoxyadenosine; 3',5'-Diamino-2',3',5'-trideoxyadenosine; 9-[(3-Amino-5-aminomethyltetrahydrofuran-2-yl)]adenine; 3',5'-Diamino-2',3',5'-trideoxy-D-erythro-pentofuranosyladenine; Dideoxyadenosine derivative, 3',5'-diamino; Adenosine, 3',5'-diamino-3',5'-dideoxy-
EINECS	Contact for details

Quality Control

Every batch of 3',5'-Diamino-3',5'-Dideoxyadenosine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support research and regulatory submissions, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing batch-specific results for purity, related substances, and residual solvents is supplied with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.