Description

1,2-Dihexadecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt is a high-purity, synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with two palmitoyl chains. This compound is critical for creating stable, biocompatible lipid bilayers and vesicles that mimic natural cell membranes. It is an essential raw material for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors, particularly for developing liposomal drug delivery systems, reconstituting membrane proteins, and formulating pulmonary surfactants.

Application

• Liposomal Drug Delivery: A key component in the formulation of liposomes for targeted and sustained release of therapeutic agents, including anticancer drugs, antibiotics, and vaccines.
• Pulmonary Surfactant Mimetics: Used in research and development of synthetic lung surfactants for treating respiratory distress syndrome (RDS) in neonates and adults.
• Membrane Protein Studies: Essential for solubilizing, stabilizing, and reconstituting integral membrane proteins in a native-like lipid environment for structural and functional analysis.
• Biomimetic Model Membranes: Serves as a fundamental building block for creating supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) used in biophysical research and biosensor development.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products as a skin-identical lipid to enhance skin barrier function, improve moisturization, and facilitate the delivery of active ingredients.
• Diagnostic Reagent Preparation: Utilized in the production of lipid-based reagents for diagnostic assays, including lateral flow tests and biosensors.

Basic Information

Product Name	1,2-Dihexadecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt
CAS No.	67232-81-9
Molecular Formula	C38H74NaO10P
Molecular Weight	744.95 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt; DPPG-Na; DPPG Sodium Salt; Phosphatidylglycerol (16:0/16:0) Sodium Salt; PG(16:0/16:0) Sodium Salt; 1,2-Dihexadecanoyl-rac-glycero-3-phosphoglycerol Sodium Salt; 1,2-Dipalmitoylphosphatidylglycerol Sodium Salt; L-α-Phosphatidylglycerol (Dipalmitoyl, Sodium Salt)
EINECS	Contact for details

Quality Control

Our 1,2-Dihexadecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and lipid profile analysis, to ensure it meets the stringent requirements for pharmaceutical and life science research. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment. We support compliance with cGMP, ICH Q7 guidelines, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate at -20°C. The product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Total Phospholipid Content)
Purity (HPLC, Main Component)	≥ 95.0%
Solubility	Soluble in chloroform, methanol; forms dispersions in water
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.