Description

1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt is a high-purity synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with two myristoyl (C14:0) fatty acid chains. This compound is critical for creating biomimetic membrane systems and serves as a fundamental building block in advanced pharmaceutical and biotechnological research. It is essential for researchers and manufacturers in the fields of liposome formulation, drug delivery systems, and membrane biophysics, where precise lipid composition dictates functionality and efficacy.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key component for constructing stable, uniform vesicles for drug encapsulation and delivery, particularly in mRNA and gene therapy applications.
• Biomimetic Membrane Models: Used to create artificial cell membranes (e.g., supported lipid bilayers, vesicles) for studying protein-lipid interactions, membrane permeability, and cellular processes.
• Pulmonary Surfactant Research: Serves as a synthetic analog in the study and development of therapeutic surfactants for treating respiratory distress syndrome.
• Pharmaceutical Excipient: Employed as a stabilizer, emulsifier, or active component in topical, parenteral, and inhaled drug products.
• Diagnostic Reagent Development: Utilized in the production of test kits and assays that rely on membrane-bound enzymes or receptors.
• Cosmetic and Dermal Formulations: Incorporated into advanced skincare products for its moisturizing and barrier-enhancing properties.

Basic Information

Product Name	1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt
CAS No.	67232-80-8
Molecular Formula	C34H66NaO10P
Molecular Weight	688.84 g/mol
Synonyms	1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt; DMPG-Na; PG(14:0/14:0) Sodium Salt; Phosphatidylglycerol (14:0) Sodium Salt; 1,2-Ditetradecanoylphosphatidylglycerol Sodium Salt; 1,2-Dimyristoylphosphatidylglycerol Sodium Salt; DMPG Sodium Salt; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol Sodium Salt
EINECS	Contact for details

Quality Control

Our 1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing specifications such as assay, fatty acid profile, and impurity limits are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Myristic acid (C14:0) ≥ 95% of total
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.