Description

4-Androsten-3,17-Dione-2,2,4,6,6,16,16-D7 is a high-purity, deuterium-labeled analog of androstenedione, a key steroid hormone precursor. This stable isotope-labeled compound is essential for providing an internal standard in mass spectrometry, ensuring the accuracy and precision of quantitative analytical methods. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and forensic toxicology labs for method development, validation, and high-throughput screening of steroid hormones and their metabolites.

Application

• Internal Standard for LC-MS/MS: Critical for the quantitative analysis of endogenous and exogenous androgens, prohormones, and their metabolites in biological matrices (e.g., serum, urine, plasma).
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetic (DMPK) studies to track the biotransformation of steroid-based drug candidates.
• Clinical Diagnostics & Endocrinology: Enables precise measurement of steroid hormone levels for diagnosing endocrine disorders, monitoring hormone replacement therapy, and anti-doping testing.
• Forensic Toxicology: Supports the detection and confirmation of anabolic-androgenic steroids (AAS) and other performance-enhancing drugs in sports doping control.
• Biochemical Research: Serves as a tracer in metabolic pathway studies to investigate steroidogenesis and enzyme activity in cell cultures or tissue samples.
• Reference Material Production: Used by certified reference material (CRM) manufacturers to create calibrated standards for laboratory quality assurance programs.

Basic Information

Item	Detail
Product Name	4-Androsten-3,17-Dione-2,2,4,6,6,16,16-D7
CAS No.	67034-85-9
Molecular Formula	C19H19D7O2
Molecular Weight	293.45 g/mol
Synonyms	Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7; Androstenedione-d7; 4-Androstenedione-2,2,4,6,6,16,16-d7; 4-AD-d7; A4-d7; [2,2,4,6,6,16,16-2H7]-4-Androstene-3,17-dione; Deuterated Androstenedione; 4-Androstene-3,17-dione (2,2,4,6,6,16,16-D7)
EINECS	Contact for details

Quality Control

Our deuterated standards are manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical stability. Each batch is characterized using advanced analytical techniques, including NMR and high-resolution mass spectrometry, to confirm deuterium incorporation and positional purity. A comprehensive Certificate of Analysis (COA) is provided, detailing assay purity, isotopic enrichment, and solvent content, supporting compliance with GLP and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvent (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.