Description

3-Hydroxy-5-Cholen-24-Oic Acid 3-Sulfate Ester CAS NO 67030-47-1 is a sulfated bile acid derivative, a key intermediate in the study of steroid metabolism and liver function. This compound is of significant value for research and development in pharmaceutical chemistry, particularly for investigating bile acid synthesis pathways and their physiological roles. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of diagnostic reagents focused on hepatobiliary and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of more complex bile acid analogs and potential therapeutic agents targeting liver and metabolic diseases.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies related to steroid sulfation and bile acid metabolism pathways.
• Diagnostic Reagent Development: Serves as a key component in the development of in-vitro diagnostic (IVD) assays for measuring bile acid profiles, which are indicators of liver function.
• Metabolite Standard: Employed in analytical laboratories as a high-purity standard for Liquid Chromatography-Mass Spectrometry (LC-MS) and other techniques to identify and quantify bile acid metabolites in biological samples.
• Cell Biology Studies: Utilized in research to study the effects of sulfated bile acids on cell signaling, membrane receptors, and transporter functions.

Basic Information

Product Name	3-Hydroxy-5-Cholen-24-Oic Acid 3-Sulfate Ester
CAS No.	67030-47-1
Molecular Formula	C24H38O6S
Molecular Weight	454.62 g/mol
Synonyms	3-Sulfolithochol-5-en-24-oic Acid; 3-Sulfolithochol-5-enic Acid; 3β-Sulfooxy-5-cholen-24-oic Acid; Lithocholic Acid 3-Sulfate (5-ene derivative); 5-Cholen-24-oic Acid, 3-hydroxy-, 3-sulfate; 3β-Hydroxy-5-cholen-24-oic Acid 3-Sulfate; 3-Sulfate Ester of 3-Hydroxy-5-cholen-24-oic Acid
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5-Cholen-24-Oic Acid 3-Sulfate Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.