Description

1-Phenoxymethyl-5-Fluorouracil is a fluorinated pyrimidine derivative, a class of compounds with significant biological activity. This compound serves as a valuable pharmaceutical intermediate and a key building block in the synthesis of more complex active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced fluorouracil prodrugs and other nucleoside analogs with potential antitumor activity.
• Oncology Research: Used in the research and development of novel chemotherapeutic agents targeting DNA synthesis in cancer cells.
• Antiviral Agent Development: Serves as a building block for compounds being investigated for antiviral properties.
• Biochemical Research: Employed in academic and industrial laboratories for studying enzyme inhibition and metabolic pathways involving pyrimidine analogs.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis of specialized fine chemicals.

Basic Information

Product Name	1-Phenoxymethyl-5-Fluorouracil
CAS No.	66910-38-1
Molecular Formula	C12H9FN2O3
Molecular Weight	248.21 g/mol
Synonyms	5-Fluoro-1-(phenoxymethyl)uracil; 1-(Phenoxymethyl)-5-fluorouracil; 5-Fluorouracil, 1-(phenoxymethyl)-; 1-Phenoxymethyl-5-fluoropyrimidine-2,4(1H,3H)-dione; NSC 339004; Fluorouracil phenoxymethyl ether
EINECS	Contact for details

Quality Control

Our 1-Phenoxymethyl-5-Fluorouracil is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.