Description

L-A-Phosphatidylcholine Divaleroyl is a synthetic, chemically defined phospholipid where the sn-1 and sn-2 positions of the glycerol backbone are esterified with valeric acid. This precise molecular structure offers superior batch-to-batch consistency and stability compared to natural lecithin extracts, making it a critical component for advanced formulation development. It is primarily sought by R&D and production teams in the pharmaceutical, nutraceutical, and advanced cosmetic industries for creating liposomes, lipid nanoparticles (LNPs), and other sophisticated delivery systems where control over lipid chemistry is paramount.

Application

• Pharmaceutical Drug Delivery: As a key structural lipid in the formulation of liposomes and lipid nanoparticles (LNPs) for targeted and sustained release of active pharmaceutical ingredients (APIs).
• mRNA Vaccine & Therapeutic Platforms: Used as a helper phospholipid or primary component in ionizable lipid systems for non-viral gene delivery vectors.
• Cosmetic Actives Delivery: Enhances skin penetration and stability of vitamins, antioxidants, and other bioactive compounds in high-performance serums and creams.
• Nutraceutical Encapsulation: For the microencapsulation of sensitive nutrients like ω-3 fatty acids or coenzyme Q10 to improve bioavailability and mask taste.
• Biomimetic Membrane Research: Serves as a model membrane component in biophysical studies and diagnostic assay development due to its defined structure.
• Cell Culture & Media Supplements: Used in specialized cell culture applications as a source of defined phospholipids.

Basic Information

Product Name	L-A-Phosphatidylcholine Divaleroyl
CAS No.	66414-34-4
Molecular Formula	C24H48NO8P
Molecular Weight	509.61 g/mol
Synonyms	1,2-Di-Valeroyl-sn-glycero-3-phosphocholine; Divaleroyl Phosphatidylcholine; PC(10:0/10:0); 1,2-Dipentanoyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine, di-C5:0; Divalerylphosphatidylcholine; L-α-Phosphatidylcholine, divaleryl-; DVP-C
EINECS	Contact for details

Quality Control

Our L-A-Phosphatidylcholine Divaleroyl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and advanced research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. For short-term use, allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.