Description

Boc-Cys(Mob)-Osu CAS NO 66413-65-8 is a highly specialized, protected amino acid derivative used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over cysteine side-chain reactivity during complex peptide assembly. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the controlled incorporation of cysteine with its thiol group protected by the 4-methoxybenzyl (Mob) moiety.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins where traditional coupling methods are employed.
• Pharmaceutical Intermediate: Serves as a crucial intermediate in the research and development of peptide-based drugs targeting various diseases.
• Bioconjugation Chemistry: Facilitates the site-specific modification of peptides and proteins for creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Research & Development: Employed in academic and industrial R&D labs for exploring novel peptide structures and their biological functions.
• Production of Cysteine-Containing Peptides: Enables the reliable synthesis of peptides containing one or multiple cysteine residues without unwanted disulfide bond formation during synthesis.

Basic Information

Product Name	Boc-Cys(Mob)-Osu
CAS No.	66413-65-8
Molecular Formula	C20H26N2O7S
Molecular Weight	438.50 g/mol
Synonyms	N-α-Boc-S-(4-Methoxybenzyl)-L-cysteine N-Hydroxysuccinimide Ester; Boc-S-(4-Methoxybenzyl)-L-cysteine N-Hydroxysuccinimide Ester; Boc-Cys(4-MeOBzl)-OSu; Boc-L-Cysteine(4-MeOBzl)-OSu ester; N-(tert-Butoxycarbonyl)-S-(4-methoxybenzyl)-L-cysteine 2,5-Dioxopyrrolidin-1-yl Ester; N-Boc-S-(p-Methoxybenzyl)-L-cysteine Succinimidyl Ester; Boc-Cys(Mob)-OSu; Boc-S-Mob-L-cysteine-OSu
EINECS	Contact for details

Quality Control

Our Boc-Cys(Mob)-Osu is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research and production applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of the pharmaceutical and biotechnology industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.