Description

(16S,19E)-19,20-Didehydro-2α-[(18E)-18,19-Didehydroalstphyllan-18-Yl]-2,7α-Dihydro-1,16-Cyclocorynan-17-Oic Acid Methyl Ester is a complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical high-purity intermediate for developing novel therapeutic agents and exploring intricate biochemical pathways. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly those targeting neurological or oncological pathways.
• Biochemical Research: Used as a reference standard or probe in studies investigating the structure-activity relationships (SAR) of complex indole alkaloids.
• Organic Synthesis: Employed in advanced multi-step synthetic routes to construct complex molecular architectures for material science or medicinal chemistry.
• Academic Research: Utilized in university and institutional laboratories for methodological development and the study of natural product analogs.
• Process Chemistry Development: Serves as a model compound for scaling up and optimizing synthetic methodologies in pilot plants.

Basic Information

Product Name	(16S,19E)-19,20-Didehydro-2α-[(18E)-18,19-Didehydroalstphyllan-18-Yl]-2,7α-Dihydro-1,16-Cyclocorynan-17-Oic Acid Methyl Ester
CAS No.	66408-46-6
Molecular Formula	C41H44N2O4
Molecular Weight	628.80 g/mol
Synonyms	Methyl (16S,19E)-19,20-didehydro-2α-[(18E)-18,19-didehydroalstphyllan-18-yl]-2,7α-dihydro-1,16-cyclocorynan-17-oate; Alstiphyllanine E Methyl Ester; 19,20-Didehydro-2α-(18,19-didehydroalstphyllan-18-yl)-2,7α-dihydro-1,16-cyclocorynan-17-oic Acid Methyl Ester; (16S,19E)-19,20-Didehydro-2α-[(18E)-18,19-didehydroalstphyllan-18-yl]-2,7α-dihydro-1,16-cyclocorynan-17-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure structural identity and high chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.