Description

13-Hydroxyoxyberberine is a specialized, oxidized derivative of the natural alkaloid berberine, characterized by the introduction of a hydroxyoxy functional group. This structural modification is of significant interest for research into novel bioactive compounds with potential pharmacological properties. It serves as a valuable high-purity reference standard and key synthetic intermediate for pharmaceutical R&D, particularly in exploring new therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug discovery and development pipelines.
• Biochemical Research: Serves as a critical intermediate or probe in studying structure-activity relationships (SAR) of berberine derivatives.
• Academic & Contract Research: Essential for universities and CROs conducting research on isoquinoline alkaloids and their modified analogs.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a building block in the synthetic pathways for potential new drug candidates.
• Analytical Chemistry: Employed as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses.

Basic Information

Product Name	13-Hydroxyoxyberberine
CAS No.	66408-27-3
Molecular Formula	C₂₀H₁₈NO₆⁺ (common ionic form) / C₂₀H₁₇NO₆
Molecular Weight	367.35 g/mol (approximate)
Synonyms	13-Hydroxyoxyberberine; 13-Hydroxy-oxyberberine; Berberine, 13-hydroxyoxy-; Oxyberberine, 13-hydroxy-; 13-Hydroxyberberine oxide; 5,6-Dihydro-9,10-dimethoxy-13-hydroxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium; 13-Hydroxy-8-oxoberberine
EINECS	Contact for details

Quality Control

We supply 13-Hydroxyoxyberberine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification, and impurity profiles is provided with each batch to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (High-Purity Grade)
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.