Description

(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-Methylpyrrolidin-2-Yl)-Methyl]-Pyrrolidine is a high-purity, chiral pyrrolidine derivative of significant interest in advanced organic synthesis. Its value lies in its role as a sophisticated building block and chiral auxiliary for the preparation of complex pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure scaffolds to develop novel active ingredients with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular targets.
• Chiral Ligand/Catalyst Synthesis: Used to construct complex ligand frameworks for asymmetric catalysis, enhancing the enantioselectivity of chemical transformations.
• Fine Chemical Building Block: Serves as a versatile scaffold for creating novel compounds in agrochemical and material science research.
• Asymmetric Synthesis: Employed as a chiral auxiliary to induce stereoselectivity in carbon-carbon and carbon-heteroatom bond-forming reactions.
• Academic & Industrial R&D: A valuable tool for method development and exploring new synthetic pathways in medicinal and process chemistry.

Basic Information

Product Name	(2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-Methylpyrrolidin-2-Yl)-Methyl]-Pyrrolidine
CAS No.	66283-23-6
Molecular Formula	C12H24N2O
Molecular Weight	212.33 g/mol
Synonyms	(-)-2-Hydroxymethyl-1-[(1-methyl-2-pyrrolidinyl)methyl]pyrrolidine; (2S,2'S)-2-(Hydroxymethyl)-1-[(1-methyl-2-pyrrolidinyl)methyl]pyrrolidine; (S,S)-(-)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine; Chiral Pyrrolidine Derivative; 1-[(1-Methyl-2-pyrrolidinyl)methyl]-2-pyrrolidinemethanol, (2S,2'S)-(-)-; (2S,2'S)-1-[(1-Methylpyrrolidin-2-yl)methyl]pyrrolidine-2-methanol
EINECS	Contact for details

Quality Control

Our (2S,2'S)-(-)-2-Hydroxymethyl-1-[(1-Methylpyrrolidin-2-Yl)-Methyl]-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.