Description

4-Methylumbelliferyl Laurate is a synthetic fluorogenic substrate specifically designed for the detection and quantification of lipase and esterase enzyme activity. This compound is a critical reagent in enzymatic assays, where its hydrolysis releases the highly fluorescent 4-methylumbelliferone, enabling sensitive and quantitative measurement. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries requiring precise enzyme kinetics and inhibitor screening.

Application

• Lipase & Esterase Activity Assays: Primary substrate for the fluorometric determination of lipase and esterase activity in research and diagnostic kits.
• Enzyme Kinetics & Inhibition Studies: Used to study reaction mechanisms, calculate kinetic parameters (Km, Vmax), and screen for potential enzyme inhibitors.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical diagnostic tests for pancreatic function and other lipid metabolism disorders.
• Biochemical Research: Employed in cell biology and microbiology to detect and localize lipolytic activity in tissues or microbial cultures.
• Pharmaceutical Quality Control: Used to test the potency and consistency of enzyme-based pharmaceutical products.
• High-Throughput Screening (HTS): Ideal for automated screening platforms in drug discovery due to its fluorogenic properties.

Basic Information

Product Name	4-Methylumbelliferyl Laurate
CAS No.	66185-71-5
Molecular Formula	C22H30O5
Molecular Weight	374.47 g/mol
Synonyms	4-MU Laurate; 4-Methylumbelliferyl Dodecanoate; 7-Hydroxy-4-methylcoumarin laurate; 4-Methylumbelliferyl Lauric Acid Ester; Lauric Acid 4-Methylumbelliferyl Ester; Dodecanoic Acid 4-Methyl-2-oxo-2H-1-benzopyran-7-yl Ester; Fluorogenic Lipase Substrate; Lipase Substrate MU-La
EINECS	Contact for details

Quality Control

Every batch of 4-Methylumbelliferyl Laurate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive fluorometric assays. A detailed Certificate of Analysis (COA) specifying identity, purity (by HPLC), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Fluorogenic Activity	Functional in standard lipase assay
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.