Description

N6-(Trifluoroacetamidohexyl)Adenosine 5''-Phosphate is a chemically modified nucleotide analog, specifically designed for advanced biochemical research and development. This compound is valued for its role as a key intermediate and tool in the study of nucleotide-binding proteins, enzyme mechanisms, and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in high-throughput screening, assay development, and the synthesis of novel bioactive molecules.

Application

• Biochemical Research: Acts as a substrate, inhibitor, or affinity ligand in enzymatic studies, particularly for kinases, dehydrogenases, and other ATP-binding proteins.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of novel nucleotide-based therapeutics and prodrugs.
• Diagnostic Assay Development: Used in the formulation of sensitive detection kits for cellular energy metabolism and enzymatic activity.
• Affinity Chromatography: Immobilized onto solid supports for the purification and isolation of specific nucleotide-binding proteins and enzymes.
• Proteomics & Molecular Biology: Employed in labeling and cross-linking experiments to study protein-nucleotide interactions.
• High-Throughput Screening (HTS): A key component in target-based screening libraries for drug discovery campaigns.

Basic Information

Product Name	N6-(Trifluoroacetamidohexyl)Adenosine 5''-Phosphate
CAS No.	66060-76-2
Molecular Formula	C₁₈H₂₃F₃N₆O₉P
Molecular Weight	561.38 g/mol
Synonyms	N6-[6-(Trifluoroacetamido)hexyl]adenosine-5'-monophosphate; 5'-AMP, N6-[6-[(trifluoroacetyl)amino]hexyl]-; N6-(6-Trifluoroacetamidohexyl)-AMP; TFA-AH-AMP; Adenosine 5'-monophosphate, N6-[6-[(trifluoroacetyl)amino]hexyl]-; 5'-Adenylic acid, N6-[6-[(trifluoroacetyl)amino]hexyl]-; N6-(Trifluoroacetamidohexyl)-5'-AMP
EINECS	Contact for details

Quality Control

Our N6-(Trifluoroacetamidohexyl)Adenosine 5''-Phosphate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR and MS for structural confirmation, and stringent controls for moisture and related substances. Certificates of Analysis (COA) documenting identity, purity, and potency are provided to ensure compliance with research-grade specifications and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.