Description

Fazarabine is a synthetic nucleoside analog with significant research and pharmaceutical interest. This compound is valued for its potential as a cytostatic agent and its role in studying cellular differentiation and proliferation mechanisms. It is primarily utilized by research institutions and pharmaceutical developers engaged in oncology research and the development of novel therapeutic agents. The material is supplied to meet the stringent purity and consistency requirements of advanced chemical and life science applications.

Application

• Pharmaceutical Research & Development: As a key intermediate or active compound in preclinical studies for oncology and hematology.
• Biochemical Research: Used as a tool compound to investigate mechanisms of action related to nucleoside metabolism and DNA synthesis inhibition.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Employed in university and institutional labs for studies on cell differentiation, apoptosis, and epigenetic modulation.

Basic Information

Product Name	Fazarabine
CAS No.	65886-71-7
Molecular Formula	C12H16N4O5
Molecular Weight	296.28 g/mol
Synonyms	1-β-D-Arabinofuranosyl-5-azacytosine; 5-Aza-2'-deoxycytidine analog; Ara-AC; NSC 281272; CI-898; 1-(β-D-Arabinofuranosyl)-5-azacytosine; 5-Azacytidine arabinoside
EINECS	Contact for details

Quality Control

Our Fazarabine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.