Description

Chaetoglobosing CAS NO 65773-98-0 is a complex indole alkaloid mycotoxin produced by certain fungi, primarily of the *Chaetomium* genus. This compound is of significant interest in biochemical and pharmacological research due to its potent biological activity as a cytoskeletal disruptor, specifically inhibiting actin polymerization. It serves as a critical reference standard and research tool for scientists in the fields of cell biology, toxicology, and natural product chemistry, enabling the study of cellular processes and the development of novel bioactive agents.

Application

• Biochemical Research: Used as a potent and specific inhibitor of actin polymerization in cell biology studies to investigate cytoskeleton dynamics, cell motility, and division.
• Pharmacological Studies: Serves as a reference compound in screening for cytotoxicity and in research exploring the mechanisms of action of mycotoxins and other natural products.
• Analytical Reference Standard: Essential for the qualitative and quantitative analysis (e.g., via HPLC, LC-MS) of fungal metabolites in food safety, environmental, and pharmaceutical quality control laboratories.
• Natural Product Chemistry: A key compound for research into fungal biosynthesis pathways and for the isolation and structural elucidation of related secondary metabolites.
• Toxicology Research: Employed in studies assessing the toxicological profiles of mycotoxins and their potential impacts on human and animal health.

Basic Information

Product Name	Chaetoglobosing
CAS No.	65773-98-0
Molecular Formula	C32H36N4O5
Molecular Weight	556.66 g/mol
Synonyms	Chaetoglobosin G; Chaetoglobosin G (Chaetoglobosing); NSC 332836; 19-O-Acetylchaetoglobosin A; 3,12-Didehydro-19-O-acetyl-[11cytochalasin J]; (1S,12S,15S,18S,19S,20S,21R,22E,24S)-19-(Acetyloxy)-15,18-dihydroxy-1,12-dimethyl-10-oxo-13-oxa-4,11-diazapentacyclo[11.10.1.0²,¹¹.0⁵,¹⁰.0¹⁵,²⁰]pentacosa-2,4,6,8,22-pentaene-21-carbonitrile
EINECS	Contact for details

Quality Control

Our Chaetoglobosing is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for advanced research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant research and analytical standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.