Description

Undecaprenyl Diphosphate-n-Acetylmuramoyl-(5- Dimethylaminonaphthalene-1-Sulfonyl)Pentapeptide is a specialized, fluorescently labeled biochemical intermediate critical for studying bacterial cell wall biosynthesis. This compound matters as a key research tool, enabling the visualization and quantification of peptidoglycan assembly processes in vitro. It is primarily needed by researchers and pharmaceutical developers in the fields of antibiotic discovery, microbiology, and enzymology to investigate novel antibacterial targets and mechanisms of action.

Application

• Enzymatic Assay Substrate: Used as a high-sensitivity fluorescent substrate for MurG and other transglycosylase enzymes in kinetic studies.
• Antibiotic Mechanism Research: Essential for screening and characterizing inhibitors of the bacterial cell wall synthesis pathway, aiding in the discovery of new antibiotic classes.
• Biochemical Pathway Analysis: Enables the tracing and quantification of lipid II polymerization and peptidoglycan cross-linking in reconstituted systems.
• High-Throughput Screening (HTS): Serves as a core component in fluorescence-based HTS assays designed to identify potential antibacterial compounds from large libraries.
• Academic Research: Utilized in university and institutional labs for fundamental studies on bacterial physiology, resistance mechanisms, and cell wall biogenesis.
• Diagnostic Development: Can be applied in the development of diagnostic tools for detecting specific enzymatic activities associated with bacterial pathogens.

Basic Information

Product Name	Undecaprenyl Diphosphate-n-Acetylmuramoyl-(5- Dimethylaminonaphthalene-1-Sulfonyl)Pentapeptide
CAS No.	65717-73-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dansyl-Lipid II; UDP-MurNAc-pentapeptide:Dolichyl Diphosphate N-Acetylmuramoyltransferase Substrate; Fluorescent Lipid II; C55-PP-MurNAc(DNS)-pentapeptide; Undecaprenyl-diphosphoryl-MurNAc-(DNS)-pentapeptide; 5-Dimethylaminonaphthalene-1-sulfonyl labeled Lipid II; N-dansyl pentapeptide phosphoundecaprenol
EINECS	Contact for details

Quality Control

Our Undecaprenyl Diphosphate-n-Acetylmuramoyl-(5- Dimethylaminonaphthalene-1-Sulfonyl)Pentapeptide is produced under stringent conditions suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and performance in sensitive biochemical assays. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 90%
Solubility	Soluble in chloroform/methanol/water mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.