Description

Corticosterone Nitroxide is a stable nitroxide radical derivative of the endogenous glucocorticoid corticosterone. This compound is of significant value as a spin label and probe in biophysical and biochemical research, particularly in electron paramagnetic resonance (EPR) spectroscopy. It is primarily utilized by research institutions, pharmaceutical R&D departments, and advanced material scientists studying membrane dynamics, protein structure, and oxidative stress mechanisms.

Application

• As a spin label in Electron Paramagnetic Resonance (EPR) spectroscopy for studying biomolecular structure and dynamics.
• Probe for investigating steroid hormone interactions with receptors and membranes.
• Research tool for analyzing lipid bilayer properties and membrane fluidity.
• Model compound in the study of nitroxide radicals and their stability.
• Potential use in the development of contrast agents or sensors.
• Biochemical research on glucocorticoid pathways and related oxidative processes.

Basic Information

Product Name	Corticosterone Nitroxide
CAS No.	65402-12-2
Molecular Formula	C₂₁H₂₉NO₄
Molecular Weight	359.46 g/mol
Synonyms	11-Dehydrocorticosterone Nitroxide; 11-Dehydrocorticosterone Nitroxyl Radical; Corticosterone, 11-dehydro-, nitroxide; 17-Deoxycortisone Nitroxide; 4-Pregnen-11-dehydrocorticosterone-21-ol-3,20-dione Nitroxide; Nitroxide derivative of Corticosterone; EPR Probe Corticosterone
EINECS	Contact for details

Quality Control

Our Corticosterone Nitroxide is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant Good Manufacturing Practice (GMP) principles for laboratory chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity, prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to Orange Crystalline Powder
Identification (IR)	Conforms to Structure
Purity (HPLC)	≥ 95.0%
EPR Signal	Characteristic triplet spectrum
Solubility	Soluble in common organic solvents (e.g., DMSO, Chloroform, Ethanol)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.