Description

Hexadecaisoleucinomycin is a complex, macrocyclic peptide antibiotic belonging to the valinomycin family. This compound is valued for its potent and selective ionophoric activity, particularly its ability to transport potassium ions across lipid membranes. It serves as a critical research tool in biochemistry and pharmacology for studying ion transport mechanisms, membrane biophysics, and as a model for designing novel ionophores. Industries engaged in advanced life science research, antimicrobial development, and specialized chemical synthesis are the primary users of this high-purity biochemical.

Application

• Biochemical Research: Used as a model ionophore to study potassium ion (K+) transport across artificial and biological membranes.
• Membrane Biophysics: A key tool for investigating membrane potential, permeability, and the function of ion channels.
• Antimicrobial Studies: Serves as a reference compound in research exploring the mechanism of action of macrocyclic antibiotic ionophores.
• Pharmacology: Employed in research related to mitochondrial function and cellular apoptosis due to its ability to disrupt ion gradients.
• Chemical Synthesis: Acts as a sophisticated intermediate or template for the synthesis of novel macrocyclic compounds with tailored ion selectivity.
• Analytical Standards: Provides a high-purity reference standard for analytical methods such as HPLC and mass spectrometry in quality control laboratories.

Basic Information

Product Name	Hexadecaisoleucinomycin
CAS No.	65230-10-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hexadecaisoleucinomycin; 16-Isoleucinomycin; Iso-16-Valinomycin; Cyclo[-(D-Val-L-Lac-L-Val-D-Hyi)₄-] (Isoleucine variant); Macrocyclic isoleucinomycin; Potassium ionophore I; Antibiotic A-204; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our Hexadecaisoleucinomycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Biological Activity (Ionophore Assay)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.