Description

1-Naphthyl-α-D-Galactopyranoside is a specialized chromogenic and fluorogenic substrate used in enzymatic assays. This compound is critical for the detection and quantification of α-galactosidase activity, a key enzyme in biochemical research and diagnostic applications. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biotechnology companies focused on enzyme kinetics, genetic screening, and lysosomal storage disorder research.

Application

• Enzymatic Substrate for α-Galactosidase: Used as a specific chromogenic substrate in spectrophotometric assays to measure α-galactosidase enzyme activity.
• Diagnostic Reagent Manufacturing: A key raw material in the production of diagnostic kits for conditions like Fabry disease, where α-galactosidase activity is a primary biomarker.
• Biochemical Research: Employed in laboratory research to study enzyme kinetics, inhibition, and purification processes of α-galactosidase.
• Microbiology and Cell Biology: Used in histochemistry and cell-based assays to visualize and localize α-galactosidase activity in tissues and cell cultures.
• Quality Control in Bioprocessing: Serves as a standard reagent for monitoring the activity of α-galactosidase enzymes produced via fermentation or recombinant technology.
• High-Throughput Screening (HTS): Applicable in drug discovery platforms to identify modulators (activators or inhibitors) of α-galactosidase for therapeutic development.

Basic Information

Product Name	1-Naphthyl-α-D-Galactopyranoside
CAS No.	65174-63-2
Molecular Formula	C16H18O6
Molecular Weight	306.31 g/mol
Synonyms	α-D-Galactopyranoside, 1-naphthyl; 1-Naphthyl α-D-galactopyranoside; α-Galactosidase Substrate; 6-(1-Naphthyl)-α-D-galactopyranoside; Naphthyl-α-D-galactoside; 1-Naphthol-α-D-galactoside; p-Nitrophenyl-α-D-galactopyranoside analog (chromogenic); α-Galactosidase Chromogenic Substrate
EINECS	Contact for details

Quality Control

Our 1-Naphthyl-α-D-Galactopyranoside is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive biochemical applications. Each lot is tested to confirm identity, purity, and performance as an enzymatic substrate. Certificates of Analysis (COA) documenting comprehensive testing results, including assay by HPLC and spectral identification, are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Performance (Enzymatic)	Suitable for use as α-galactosidase substrate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.