Description

1-o-Hexadecyl-2-Acetyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid analog, specifically a platelet-activating factor (PAF) analog. This compound is a critical biochemical tool and a key intermediate in advanced research and development. It is essential for researchers and manufacturers in the life sciences sector who require precise and reliable bioactive lipids for studying cell signaling pathways, inflammation, and for developing novel therapeutic agents and diagnostic assays.

Application

• Biochemical Research: As a standard and agonist in platelet-activating factor (PAF) receptor studies and signal transduction research.
• Pharmaceutical Development: A key intermediate in the synthesis of novel anti-inflammatory drugs and PAF receptor antagonists.
• Cell Biology: Used to investigate cellular responses, including platelet aggregation, neutrophil activation, and inflammatory mediator release.
• Diagnostic Reagent Manufacturing: A critical component in the formulation of specialized assay kits for studying inflammatory and allergic responses.
• Lipidomics & Metabolomics: Serves as a reference standard for the identification and quantification of complex lipids in biological samples.
• Academic Research: Fundamental tool in university and institutional labs for cardiovascular, immunological, and pharmacological studies.

Basic Information

Item	Detail
Product Name	1-o-Hexadecyl-2-Acetyl-Sn-Glycero-3-Phosphocholine
CAS No.	65154-06-5
Molecular Formula	C26H54NO7P
Molecular Weight	523.68 g/mol
Synonyms	PAF C-16; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; Platelet-Activating Factor C-16; C16 PAF; AGEPC (1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine); 1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-O-hexadecyl-2-acetyl-; Lyso-PAF C-16 Acetate
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Acetyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic and moisture-sensitive; ensure containers are sealed tightly after each use to minimize exposure to air and humidity. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.