Description

n-(4-(((2,4-Diamino-6-Pteridinyl)Methyl)Amino)-2-Methoxybenzoyl)-L-Glu Tamic Acid is a high-purity, complex folate derivative with significant biochemical relevance. This compound is critical for research and development in advanced pharmaceutical synthesis and metabolic studies. It is primarily utilized by manufacturers and research institutions in the life sciences sector for developing targeted therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antifolate drugs and targeted cancer therapeutics.
• Biochemical Research: Used as a reference standard and reagent in enzymatic studies, particularly those involving folate-dependent metabolic pathways.
• Diagnostic Development: Serves as a crucial component in the development of diagnostic assays and kits for measuring folate levels or related enzymatic activity.
• Nutraceutical R&D: Investigated for potential applications in advanced nutritional supplements and specialized medical foods.
• Academic Research: Employed in university and institutional labs for fundamental research in chemistry, biochemistry, and molecular biology.

Basic Information

Product Name	n-(4-(((2,4-Diamino-6-Pteridinyl)Methyl)Amino)-2-Methoxybenzoyl)-L-Glu Tamic Acid
CAS No.	65118-34-5
Molecular Formula	C₂₀H₂₃N₉O₆
Molecular Weight	485.46 g/mol
Synonyms	L-Glutamic Acid, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]-2-methoxybenzoyl]-; 4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]-2-methoxybenzoic acid glutamate; Methotrexate Glutamate Derivative; Folate Analog Intermediate; PT523 (research code); NSC 363812; 2-Methoxy-4-(((2,4-diaminopteridin-6-yl)methyl)amino)benzoyl-L-glutamic acid
EINECS	Contact for details

Quality Control

Our n-(4-(((2,4-Diamino-6-Pteridinyl)Methyl)Amino)-2-Methoxybenzoyl)-L-Glu Tamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.