Description

1-Palmitoyl-2-ω-(2-Diazo-3,3,3-Trifluoropropionyloxy)Lauroyl-Sn-Glycero-3-Phosphocholine is a specialized, photoactivatable phospholipid derivative designed for advanced biochemical research and pharmaceutical development. This compound is critical for studying membrane dynamics, protein-lipid interactions, and for the site-specific labeling of biological systems. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic developers working in areas such as lipidomics, probe development, and targeted drug delivery systems.

Application

• Photoaffinity Labeling: Acts as a critical cross-linking agent for identifying and mapping protein binding sites within lipid membranes.
• Membrane Biophysics Research: Used to study lipid bilayer properties, phase transitions, and the incorporation of fluorinated moieties into membranes.
• Fluorescent Probe Synthesis: Serves as a key intermediate for creating advanced, photoactivatable fluorescent lipid probes for live-cell imaging.
• Phospholipase Substrate: Employed as a specialized substrate in enzymatic assays to study phospholipase activity and specificity.
• Drug Delivery System Development: Investigated for the formulation of targeted liposomal and nanoparticle-based delivery vehicles.
• Metabolic Tracing: Utilized in lipid metabolism studies to trace the incorporation and turnover of modified phospholipids.

Basic Information

Product Name	1-Palmitoyl-2-ω-(2-Diazo-3,3,3-Trifluoropropionyloxy)Lauroyl-Sn-Glycero-3-Phosphocholine
CAS No.	65114-55-8
Molecular Formula	C₄₄H₈₁F₃N₃O₁₀P
Molecular Weight	900.10 g/mol
Synonyms	Diazotrifluoropropionyl Phosphatidylcholine; Photoactivatable PC Lipid; 1-Palmitoyl-2-(11-((2-diazo-3,3,3-trifluoropropanoyl)oxy)undecanoyl)-sn-glycero-3-phosphocholine; TFP-Diazirine-PC; Trifluoropropyl Diazirine Phospholipid; PC(16:0/11:0(Diazirine-TFP)); Diazirine-Modified Phosphatidylcholine; Light-Activatable Lipid Probe
EINECS	Contact for details

Quality Control

Every batch of our 1-Palmitoyl-2-ω-(2-Diazo-3,3,3-Trifluoropropionyloxy)Lauroyl-Sn-Glycero-3-Phosphocholine is manufactured and analyzed under strict quality protocols to ensure high purity and batch-to-batch consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dedicated, moisture-free environment. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.