Description

n-[3-(2-Furyl)Acryloyl]-L-Phenylalanyl-Glycyl-Glycine is a synthetic peptide derivative that serves as a crucial building block and research tool in advanced biochemical and pharmaceutical development. This compound is valued for its specific structural motif, which is integral to studying enzyme-substrate interactions and designing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, protease inhibitor development, and medicinal chemistry programs.

Application

• Protease Inhibitor Research: Used as a substrate analog or inhibitor scaffold in the study of serine and cysteine proteases.
• Medicinal Chemistry: Serves as a key intermediate in the synthesis of potential therapeutic peptides targeting various diseases.
• Biochemical Assay Development: Employed in the design and calibration of enzymatic activity assays and high-throughput screening (HTS) platforms.
• Structure-Activity Relationship (SAR) Studies: Provides a core structure for modifying side chains to analyze and optimize biological activity and selectivity.
• Academic & Institutional Research: A fundamental reagent for investigating peptide bond formation, stability, and degradation pathways.

Basic Information

Product Name	n-[3-(2-Furyl)Acryloyl]-L-Phenylalanyl-Glycyl-Glycine
CAS No.	64967-39-1
Molecular Formula	C20H21N3O6
Molecular Weight	399.40 g/mol
Synonyms	FAPPG; N-[(E)-3-(2-Furyl)prop-2-enoyl]-L-phenylalanylglycylglycine; FA-Phe-Gly-Gly-OH; Furylacryloyl-Phe-Gly-Gly; 2-Furanacryloyl-L-phenylalanylglycylglycine; N-[3-(2-Furanyl)-1-oxo-2-propenyl]-L-phenylalanylglycylglycine; Substrate for Chymotrypsin
EINECS	Contact for details

Quality Control

Our n-[3-(2-Furyl)Acryloyl]-L-Phenylalanyl-Glycyl-Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.