Description

3Alpha-Hydroxy-5Beta-Cholan-24-Oic Acid n-[2-Sulfoethyl]Amide 3-Sulfate Disodium Salt is a high-purity, synthetically derived bile acid derivative with a complex, multi-functional structure. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector focusing on hepatobiliary and metabolic pathways.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Biochemical Research: Used as a reference standard and probe in studies of bile acid transport, receptor binding (e.g., FXR, TGR5), and signaling pathways.
• Analytical Standard: Serves as a high-purity calibrant for quantitative analysis (HPLC, LC-MS) in bioanalytical and pharmacokinetic studies.
• Enzyme Substrate/Analog: Potential substrate or inhibitor for enzymes involved in bile acid metabolism and conjugation.
• Diagnostic Reagent Development: Used in the formulation of reagents and kits for clinical diagnostics related to liver function.

Basic Information

Product Name	3Alpha-Hydroxy-5Beta-Cholan-24-Oic Acid n-[2-Sulfoethyl]Amide 3-Sulfate Disodium Salt
CAS No.	64936-83-0
Molecular Formula	C₂₆H₄₂NNa₂O₁₀S₂
Molecular Weight	654.72 g/mol
Synonyms	Disodium 3α-Hydroxy-5β-cholan-24-oyl taurine 3-sulfate; Tauro-3-sulfolithocholic acid disodium salt; 3α-Sulfotauro-5β-cholan-24-oic acid disodium salt; N-(2-Sulfoethyl)-3-sulfocholamide disodium salt; Taurolithocholic acid 3-sulfate disodium salt; TLCS disodium; TLC-SO₃Na₂
EINECS	Contact for details

Quality Control

Every batch of our 3Alpha-Hydroxy-5Beta-Cholan-24-Oic Acid n-[2-Sulfoethyl]Amide 3-Sulfate Disodium Salt is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to support research and regulatory requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.