Description

2'-Dansyl-Cyclic Amp CAS NO 64691-10-7 is a high-purity, fluorescently labeled derivative of cyclic adenosine monophosphate (cAMP), a critical secondary messenger in cellular signaling pathways. This compound is specifically engineered for advanced biochemical research, offering superior sensitivity and specificity for detection and quantification in complex biological matrices. It is an essential reagent for researchers and scientists in pharmaceutical development, molecular biology, and diagnostic assay manufacturing who require reliable, high-quality probes for studying intracellular signal transduction mechanisms.

Application

• Biochemical Research & Assay Development: As a fluorescent tracer in competitive binding assays (e.g., ELISA, FPIA) for cAMP quantification.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel drug candidates targeting G-protein-coupled receptors (GPCRs) and adenylate cyclase activity.
• Cell Signaling Studies: A vital tool for visualizing and measuring real-time changes in intracellular cAMP levels using fluorescence microscopy or spectroscopy.
• Diagnostic Kit Manufacturing: Serves as a key component in the production of commercial immunoassay kits for clinical and research diagnostics.
• Enzyme Activity Analysis: Employed as a substrate or probe in studies involving phosphodiesterases (PDEs) and other enzymes that modulate cAMP levels.
• Academic Research: Fundamental research in physiology, neurobiology, and endocrinology to understand cAMP-mediated cellular responses.

Basic Information

Product Name	2'-Dansyl-Cyclic Amp
CAS No.	64691-10-7
Molecular Formula	C26H29N7O11P
Molecular Weight	670.53 g/mol
Synonyms	2'-O-(5-Dimethylaminonaphthalene-1-sulfonyl)adenosine 3',5'-cyclic monophosphate; 2'-Dansyl cAMP; N6,2'-O-Bis(dansyl)adenosine 3',5'-cyclic monophosphate; Dansyl-labeled cyclic AMP; Fluorescent cAMP derivative; cAMP-Dansyl; Cyclic AMP dansyl conjugate; Adenosine 3',5'-cyclic monophosphate 2'-O-(5-dimethylaminonaphthalene-1-sulfonyl)
EINECS	Contact for details

Quality Control

Every batch of 2'-Dansyl-Cyclic Amp is manufactured under strict quality management protocols and undergoes comprehensive analytical testing to ensure identity, purity, and performance consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for research-grade biochemicals, ensuring reliability for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Extinction Coefficient	~4,300 M-1cm-1 at 340 nm
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.