Description

n-Benzoyl-2'-o-[(2-Nitrophenyl)Methyl]Adenosine CAS NO 64481-97-6 is a chemically modified nucleoside derivative, specifically a protected adenosine analog. This compound is of significant value as a key synthetic intermediate in the research and development of novel pharmaceuticals and biochemical probes. It is primarily needed by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of modified oligonucleotides for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in the study of enzyme mechanisms, particularly those involving adenosine-processing enzymes, by acting as a substrate analog or inhibitor.
• Pro-drug Development: Acts as a protected precursor molecule that can be selectively deprotected to release active pharmaceutical ingredients in targeted drug delivery systems.
• Oligonucleotide Synthesis: Employed in the preparation of modified RNA or DNA strands for antisense therapy, siRNA, and diagnostic applications.
• Chemical Biology Tool: Utilized to create affinity probes or labeled nucleotides for investigating cellular processes and protein-nucleic acid interactions.

Basic Information

Product Name	n-Benzoyl-2'-o-[(2-Nitrophenyl)Methyl]Adenosine
CAS No.	64481-97-6
Molecular Formula	C25H22N6O6
Molecular Weight	502.48 g/mol
Synonyms	2'-O-[(2-Nitrophenyl)methyl]adenosine N-benzoyl derivative; N-Benzoyl-2'-O-(2-nitrobenzyl)adenosine; 2'-O-(2-Nitrobenzyl)-N-benzoyladenosine; Bz-2'-O-NB-Adenosine; Adenosine, 2'-O-[(2-nitrophenyl)methyl]-, N-benzoyl-; Protected Adenosine Derivative; 64481-97-6; 2'-O-(o-Nitrobenzyl)-N-benzoyladenosine
EINECS	Contact for details

Quality Control

Our n-Benzoyl-2'-o-[(2-Nitrophenyl)Methyl]Adenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.