Description

(2R)-4α-(Dimethylamino)-3,4,5,6,11,12,13,14-Octahydro-3β,5β,8,10,13α-Pentahydroxy-11β-Methoxy-6,13-Dimethyl-2α,6α-Epoxy-2H-Naphthaceno[1,2-B]Oxocin-9,16-Dione is a complex tetracycline-class derivative with a highly functionalized polycyclic structure. This compound is of significant interest for its role as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis and study of novel antibiotics and other bioactive molecules. The precise stereochemistry and functional groups are critical for its biological activity and utility in chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel tetracycline antibiotics and analogs.
• Research & Development: Used as a high-purity reference standard in analytical method development, quality control, and pharmacological studies.
• Chemical Biology: Employed as a molecular probe to investigate bacterial protein synthesis mechanisms and resistance pathways.
• Process Chemistry: Acts as a key intermediate for process optimization and scale-up activities in active pharmaceutical ingredient (API) manufacturing.
• Academic Research: Utilized in university and institutional labs for synthetic chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Item	Detail
Product Name	(2R)-4α-(Dimethylamino)-3,4,5,6,11,12,13,14-Octahydro-3β,5β,8,10,13α-Pentahydroxy-11β-Methoxy-6,13-Dimethyl-2α,6α-Epoxy-2H-Naphthaceno[1,2-B]Oxocin-9,16-Dione
CAS No.	64267-47-6
Molecular Formula	C27H33NO10
Molecular Weight	531.56 g/mol
Synonyms	4α-(Dimethylamino)-3,4,5,6,11,12,13,14-octahydro-3β,5β,8,10,13α-pentahydroxy-11β-methoxy-6,13-dimethyl-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-9,16-dione; (2R)-DMDOT; 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline derivative; Tetracycline intermediate 64267-47-6; 4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide derivative (stereospecific)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.