Description

Tiglylcarnitine is a specialized acylcarnitine derivative, an essential intermediate in mitochondrial fatty acid and branched-chain amino acid metabolism. Its precise quantification and high purity are critical for research and diagnostic applications focused on inborn errors of metabolism. This compound is primarily utilized by biochemical research laboratories, diagnostic kit manufacturers, and pharmaceutical development teams investigating metabolic disorders such as 3-methylcrotonyl-CoA carboxylase deficiency.

Application

• Biomarker Standard for Clinical Diagnostics: Used as a critical reference standard in LC-MS/MS assays for the accurate quantification of tiglylcarnitine in patient plasma or dried blood spots to diagnose organic acidemias.
• Metabolic Pathway Research: Serves as a key substrate or intermediate in in vitro studies to elucidate the biochemical pathways of isoleucine catabolism and related metabolic disorders.
• Pharmaceutical R&D: Employed in the development and validation of therapeutic strategies targeting specific mitochondrial enzyme deficiencies.
• Quality Control for Diagnostic Kits: Integrated into the manufacturing process of clinical diagnostic kits to ensure assay accuracy, precision, and reliability.
• Nutritional and Sports Science Studies: Investigated as a potential biomarker for assessing metabolic flux and energy metabolism under various physiological conditions.

Basic Information

Product Name	Tiglylcarnitine
CAS No.	64191-86-2
Molecular Formula	C12H23NO5
Molecular Weight	261.31 g/mol
Synonyms	(2E)-2-Methylbut-2-enoylcarnitine; L-Tiglylcarnitine; Tiglyl-L-carnitine; (3-Carboxy-2-hydroxypropyl)trimethylammonium (2E)-2-methylbut-2-enoate; 3-Methylcrotonylglycine Related Compound; 2-Methylcrotonoylcarnitine
EINECS	Contact for details

Quality Control

Our Tiglylcarnitine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the exacting standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.