Description

S-(1-Phenyl-2-Hydroxyethyl)Glutathione is a specialized glutathione derivative, a key conjugate in the study of metabolic detoxification pathways. This compound is of significant interest for its role as a model substrate in enzymatic and biochemical research related to glutathione S-transferase (GST) activity. It is primarily utilized by research institutions and pharmaceutical development teams focused on xenobiotic metabolism, biomarker discovery, and the development of analytical standards for toxicology studies.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of glutathione conjugation reactions and Phase II metabolism.
• Enzymology: Serves as a specific substrate for investigating the kinetics and specificity of Glutathione S-Transferase (GST) enzymes.
• Toxicology & Metabolite Identification: Employed in the identification and quantification of mercapturic acid pathway metabolites for toxicological assessments.
• Pharmaceutical Development: Acts as a key intermediate or reference compound in the research of drugs targeting oxidative stress and detoxification mechanisms.
• Analytical Standard: Provides a high-purity standard for HPLC, LC-MS, and other analytical methods used in bioanalytical laboratories.

Basic Information

Product Name	S-(1-Phenyl-2-Hydroxyethyl)Glutathione
CAS No.	64186-97-6
Molecular Formula	C₁₈H₂₇N₃O₇S
Molecular Weight	429.49 g/mol
Synonyms	S-(1-Phenyl-2-hydroxyethyl)glutathione; S-(2-Hydroxy-2-phenylethyl)glutathione; Glutathione, S-(1-phenyl-2-hydroxyethyl)-; Glutathione S-(1-phenyl-2-hydroxyethyl) ester; GST Substrate Analog; Phenylhydroxyethyl Glutathione Conjugate; 1-Phenyl-2-hydroxyethyl glutathione thioether
EINECS	Contact for details

Quality Control

Our S-(1-Phenyl-2-Hydroxyethyl)Glutathione is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, with specifications tailored to meet the rigorous demands of analytical and biochemical laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.