Description

Succinimidyl n-Methylanthranilate (CAS NO 64156-72-5) is a highly reactive amine-reactive crosslinking reagent, primarily used for the conjugation of biomolecules. Its core value lies in its ability to form stable amide bonds with primary amines, enabling the precise labeling and modification of proteins, peptides, and other amine-containing compounds. This compound is essential for researchers and manufacturers in the fields of bioconjugation, proteomics, diagnostic assay development, and antibody-drug conjugate (ADC) synthesis.

Application

• Bioconjugation and Protein Labeling: For attaching fluorescent dyes, biotin, or other probes to antibodies, enzymes, and peptides for imaging and detection.
• Antibody-Drug Conjugate (ADC) Linker Chemistry: Serves as a key intermediate in the synthesis of cleavable or non-cleavable linkers for targeted cancer therapies.
• Diagnostic Reagent Manufacturing: Used in the development of enzyme-linked immunosorbent assays (ELISA), lateral flow assays, and other immunoassay components.
• Surface Functionalization: For modifying nanoparticles, microspheres, biosensor chips, and other solid supports with amine-reactive groups.
• Peptide Synthesis and Modification: As a building block or activating agent in solid-phase peptide synthesis (SPPS) for introducing specific functionalities.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers for biomedical and material science applications.

Basic Information

Product Name	Succinimidyl n-Methylanthranilate
CAS No.	64156-72-5
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	N-Methylanthranilic Acid N-Hydroxysuccinimide Ester; 2-[[(2-Methylphenyl)amino]carbonyl]benzoic Acid N-Hydroxysuccinimide Ester; N-Succinimidyl N-Methylanthranilate; N-Methylanthranilic Acid Succinimidyl Ester; NHS Ester of N-Methylanthranilic Acid; SMA; Succinimidyl Ester of N-Methylanthranilic Acid
EINECS	Contact for details

Quality Control

Our Succinimidyl n-Methylanthranilate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.