Description

Lobeline Hydrochloride, 97% is a high-purity alkaloid salt derived from *Lobelia inflata*, widely recognized for its pharmacological activity. This compound is essential for research and development in the pharmaceutical and life sciences sectors, where consistent quality and reliable supply are paramount. It serves as a critical intermediate and reference standard for scientists and manufacturers developing treatments for respiratory conditions and smoking cessation aids, as well as for neurological research.

Application

• Pharmaceutical Intermediates: A key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs) for respiratory stimulants and smoking deterrent formulations.
• Reference Standards & Analytical Testing: Used as a certified reference material (CRM) in HPLC, GC, and other analytical methods for quality control and method validation in pharmaceutical laboratories.
• Biochemical & Neurological Research: Employed in *in vitro* and *in vivo* studies to investigate nicotinic acetylcholine receptor (nAChR) interactions, neurotransmitter release, and potential therapeutic applications for addiction and neurodegenerative diseases.
• Veterinary Medicine: Utilized in the development of respiratory treatments and stimulants for animal healthcare applications.
• Academic & Contract Research: Serves as a vital reagent for universities and CROs (Contract Research Organizations) conducting pharmacological and toxicological studies.

Basic Information

Product Name	Lobeline Hydrochloride, 97%
CAS No.	63990-84-1
Molecular Formula	C22H27NO2 • HCl
Molecular Weight	373.92 g/mol
Synonyms	Lobeline HCl; α-Lobeline hydrochloride; 2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidyl]-1-phenylethanone hydrochloride; L-Lobeline hydrochloride; (-)-Lobeline hydrochloride; Lobelia Alkaloid; (R-(R*,S*))-2-((1-Methyl-6-(2-phenylethyl)-2-piperidinyl)methyl)-1-phenylethanone hydrochloride
EINECS	Contact for details

Quality Control

Every batch of our Lobeline Hydrochloride, 97% is manufactured and tested under strict quality management systems to ensure it meets the high standards required for research and pharmaceutical applications. Our products undergo rigorous quality testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	97.0% min.
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 1.0% Total impurities: ≤ 3.0%
Solubility	Soluble in water and alcohol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.