Description

1',3'-Bis[1,2-Dimyristoyl-Sn-Glycero-3-Phospho]-Sn-Glycerol (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a cardiolipin analog, essential for creating biomimetic membrane systems. Its value lies in providing a defined, consistent structural component critical for advanced research and formulation stability. This compound is primarily needed by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic researchers working on liposomal drug delivery, membrane protein studies, and mitochondrial function assays.

Application

• Liposomal Drug Delivery Systems: As a key structural phospholipid for formulating stable, targeted liposomes and nanoparticles.
• Biomimetic Membrane Research: For constructing model lipid bilayers and vesicles to study membrane biophysics, protein-lipid interactions, and transport mechanisms.
• Diagnostic Reagent Formulation: Used in the production of reagents for clinical diagnostics, particularly in assays related to autoimmune diseases (e.g., anti-cardiolipin antibody tests).
• Mitochondrial Studies: Serving as a critical component in research focused on mitochondrial membrane structure, function, and associated bioenergetics.
• Excipient in Advanced Formulations: Potential use as a functional excipient in niche pharmaceutical formulations requiring specific membrane-fusion properties.
• Reference Standard: Acts as an analytical standard for quality control and method development in lipidomics and related analytical fields.

Basic Information

Item	Details
Product Name	1',3'-Bis[1,2-Dimyristoyl-Sn-Glycero-3-Phospho]-Sn-Glycerol (Sodium Salt)
CAS No.	63988-21-6
Molecular Formula	C65H124Na2O17P2
Molecular Weight	1261.66 g/mol (approx.)
Synonyms	Tetramyristoyl Cardiolipin (Sodium Salt); Cardiolipin (14:0)4 Sodium Salt; 1,3-Bis(1,2-ditetradecanoyl-sn-glycero-3-phospho)-sn-glycerol Sodium Salt; CL(56:0) Sodium Salt; DMPC-Cardiolipin; TMCL; Bis(1,2-dimyristoyl-sn-glycero-3-phospho)-1,3-sn-glycerol Sodium Salt
EINECS	Contact for details

Quality Control

Our 1',3'-Bis[1,2-Dimyristoyl-Sn-Glycero-3-Phospho]-Sn-Glycerol (Sodium Salt) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and critical impurities. We adhere to cGMP principles where applicable, and specifications can be aligned with customer-specific requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 3.0 %
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.