Description

(5S)-4,5-Epoxy-5-Methoxy-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral intermediate and a valuable scaffold for developing novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized alkaloids and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex natural products and novel drug candidates targeting neurological and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities with potential biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories studying akuammilan or related indole alkaloids.
• Organic Synthesis: Employed in advanced synthetic chemistry for exploring novel cyclization reactions and constructing complex polycyclic frameworks.
• Biochemical Research: Investigated for its potential interactions with biological systems and enzymes due to its intricate alkaloid structure.

Basic Information

Product Name	(5S)-4,5-Epoxy-5-Methoxy-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester
CAS No.	63964-36-3
Molecular Formula	C22H26N2O5
Molecular Weight	398.46 g/mol
Synonyms	Methyl (5S)-4,5-epoxy-5-methoxy-6α,21α-cyclo-4,5-secoakuammilan-17-oate; 4,5-Secoakuammilan Derivative; 17-Methoxycarbonyl-4,5-epoxy-5-methoxy-6α,21α-cyclo-4,5-secoakuammilan; Akuammilan Alkaloid Intermediate; (5S)-4,5-Epoxy-5-methoxy-6α,21α-cyclo-4,5-secoakuammilan-17-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (5S)-4,5-Epoxy-5-Methoxy-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to meet the exacting standards of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.